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313 Pleasant St., Watertown, MA, 02472, USA
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Apredica provides preclinical contract testing services for the evaluation and optimization of the ADME, Toxicity, and Pharmacokinetic properties of drug candidates early in the drug-discovery process. They also provide in vitro testing services for cosmetics, agrochemicals, and other products for REACH compliance.

Apredica offers three levels of service for the pre-GLP pharmacokinetic (PK) studies needed subsequent to the early ADMET phase of drug development:

In-Life Phase: Full or fast pharmacokinetics services. While standard industry-accepted protocols are available, Apredica can support fully customized PK study designs. Plasma, blood, or other tissues can be collected and prepared to your specifications. All PK studies are conducted under strict IACUC guidelines in an AAALAC-approved lab and require IACUC approval.

Bioanalytical Method Development: Bioanalytical methods can be developed for your test agent in any biological matrix. The limits of quantitation and detection as well as recovery from many matrices can be determined using our state-of-the-art LC/MS/MS analytical equipment. More about our bioanalytical methodology.

Bioanalysis: The amount of test agent in the collected plasma or tissue is analyzed and quantified using LC/MS/MS.