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Microtest Laboratories Inc. USP Antibiotic Testing

Address
104 Gold Street, Agawam, MA, 01001, USA
Type of Facility
Other
Telephone
800-631-1680
Fax
413-789-4334
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Owner
Microtest is a highly experienced provider of USP antibiotic testing services to evaluate the potency of an antibiotic against USP standards in whether a pharmaceutical substance or medical device exhibits antibacterial activity. An antiobiotic present in a sample that is not neutralized can render later testing less useful by making it unlikely a low level of inoculant will be detected. If inhibition is found the test method must be modified to neutralize any antibiotic present.
The zone of inhibition is a qualitative test. Samples — usually 100 g or 100 mL each — are submitted in sterile containers. Their microbiologists cultivate these samples in a nutrient (agar) medium. Any zones wherein bacterial growth is inhibited are measured, and compared to controls.
Microtest also conducts quantitative testing to measure microgram quantities of antibiotics in biological products, drug products, or animal tissue
The agar growth medium Microtest uses in the relevant tests above consists of ATCC strains, all quality-controlled under our rigorous GMP program to ensure optimal recovery of specific organisms. And as usual with Microtest (though not with many other laboratories in the field), highly experienced, certified regulatory microbiologists perform all antibiotic testing procedures.